| Identification | Back Directory | [Name]
N-Boc-O-(2-azidoethyl)-L-tyrosine | [CAS]
1434445-10-9 | [Synonyms]
Boc-L-Tyr(2-azidoethyl)-OH
N-Boc-O-(2-azidoethyl)-L-tyrosine | [Molecular Formula]
C16H22N4O5 | [MDL Number]
MFCD31704928 | [MOL File]
1434445-10-9.mol | [Molecular Weight]
350.38 |
| Hazard Information | Back Directory | [Uses]
Boc-L-Tyr(2-azidoethyl)-OH (N-Boc-O-(2-azidoethyl)-L-tyrosine) is a click chemistry reagent containing an azide group[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. | [References]
[1] Xin BT, et, al. Structure-Based Design of Inhibitors Selective for Human Proteasome β2c or β2i Subunits. J Med Chem. 2019 Feb 14;62(3):1626-1642. DOI:10.1021/acs.jmedchem.8b01884 |
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