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143716-62-5

143716-62-5 Structure

143716-62-5 Structure
IdentificationBack Directory
[Name]

2',4'-dinitrophenyl 2-deoxy-2-fluorogalactopyranoside
[CAS]

143716-62-5
[Synonyms]

2,4-Dinitrophenyl 2-Deoxy-2-fluoro-
2,4-Dinitrophenyl 2-Deoxy-2-fluoro-β-D-galactoside
2,4-Dinitrophenyl 2-Deoxy-2-fluoro-β-D-galactoside
2',4'-dinitrophenyl 2-deoxy-2-fluorogalactopyranoside
β-D-Galactopyranoside, 2,4-dinitrophenyl 2-deoxy-2-fluoro-
[Molecular Formula]

C12H13FN2O9
[MDL Number]

MFCD31562872
[MOL File]

143716-62-5.mol
[Molecular Weight]

348.24
Chemical PropertiesBack Directory
[Melting point ]

168-170°C
[storage temp. ]

Amber Vial, Refrigerator
[solubility ]

Methanol (Slightly)
[form ]

Solid
[color ]

Off-White to Pale Yellow
Hazard InformationBack Directory
[Chemical Properties]

Off-White to Pale Yellow Solid
[Uses]

2',4'-Dinitrophenyl 2-deoxy-2-fluorogalactopyranoside is fluorinated and deoxygenated glycosides as mechanistic probes of Escherichia coli (lacZ) β-galactosidase. By use of the slow substrate 2,4-dinitrophenyl-2-deoxy-2-fluoro-β-D-galactopyranoside, a glycosyl enzyme intermediate has been trapped on the enzyme.
[Uses]

Fluorinated and deoxygenated glycosides as mechanistic probes of Escherichia coli (lacZ) β-galactosidase. By use of the slow substrate 2,4-dinitrophenyl-2-deoxy-2-fluoro-β-D-galactopyranoside, a glycosyl enzyme intermediate has been trapped on the enzyme. Glu-268 was identified as the catalytic nucleophile of human lysosomal β-galactosidase precursor.
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