| Identification | Back Directory | [Name]
TCO-PNB Ester | [CAS]
1438415-89-4 | [Synonyms]
TCO-PNB Ester
TCO-PNB ester >=95%
TCO*E - active ester (p-NPC) / equatorial
(E)-cyclooct-4-en active ester / TCO/A- active ester (p-NPC) / axial
(E)-cyclooct-4-en active ester / TCO4 / A- active ester (p-NPE) / axial | [Molecular Formula]
C15H17NO5 | [MDL Number]
MFCD31715315 | [MOL File]
1438415-89-4.mol | [Molecular Weight]
291.3 |
| Chemical Properties | Back Directory | [Boiling point ]
433.9±45.0 °C(Predicted) | [density ]
1.24±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
powder or chunks | [color ]
Off-white to light yellow | [InChI]
1S/C15H17NO5/c17-15(20-13-6-4-2-1-3-5-7-13)21-14-10-8-12(9-11-14)16(18)19/h1-2,8-11,13H,3-7H2 | [InChIKey]
FJMMADPCDJNXAH-UHFFFAOYSA-N | [SMILES]
O=C(OC1CCC/C=C/CC1)OC2=CC=C([N+]([O-])=O)C=C2 |
| Hazard Information | Back Directory | [Description]
TCO-PNB Ester contains two reactive substituents. The PNB ester is reactive with amine groups. TCO group can participate in Click Chemistry reactions with tetrazine and can be used to label antibodies and proteins. | [Uses]
TCO-PNB ester (trans-Cyclooctene-p-nitrobenzyl ester) has a p-nitrobenzyl (PNB) ester group that is amine reactive and a trans-cyclooctene (TCO) group that is reactive with tetrazines. TCO-PNB ester is supplied as a single axial (major) diastereomer. This specially formulated crystalline material provides easy handling and extended shelf life. | [reaction suitability]
reaction type: click chemistry
reagent type: cross-linking reagent | [IC 50]
Alkyl/ether |
|
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Bide Pharmatech Ltd.
|
| Telephone: |
400-1647117 13681763483 |
| Website: |
https://www.bidepharm.com/ |
|