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144060-40-2

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144060-40-2 Structure

144060-40-2 Structure
IdentificationBack Directory
[Name]

Febuxostat Bromo Impurity
[CAS]

144060-40-2
[Synonyms]

Febuxostat-4
Febuxostat Bromo Impurity
3-Descyano 3-Bromo-febuxostat
2-(3-bromo-4-isobutoxyphenyl)
2-(3-bromo-4-isobutoxyphenyl)-4- methylthiazole-5-carboxylic acid
2-(3-bromo-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid
5-Thiazolecarboxylic acid, 2-[3-bromo-4-(2-methylpropoxy)phenyl]-4-methyl-
Febuxostat Impurity 12/Febuxostat Bromo Impurity/2-(3-bromo-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid
[Molecular Formula]

C15H16BrNO3S
[MOL File]

144060-40-2.mol
[Molecular Weight]

370.26
Chemical PropertiesBack Directory
[Boiling point ]

510.9±60.0 °C(Predicted)
[density ]

1.444±0.06 g/cm3(Predicted)
[pka]

2.60±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

3-Descyano 3-Bromo-febuxostat is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.
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