| Identification | Back Directory | [Name]
AM-9074 >=98% (HPLC) | [CAS]
1442677-92-0 | [Synonyms]
AM-9074 >=98% (HPLC)
Urea, N-[4-[(5-methoxy-3-pyridinyl)oxy]-5-[(3R)-tetrahydro-2H-pyran-3-yl]-2-pyridinyl]-N'-methyl- | [Molecular Formula]
C18H22N4O4 | [MDL Number]
MFCD31697714 | [MOL File]
1442677-92-0.mol | [Molecular Weight]
358.39 |
| Chemical Properties | Back Directory | [Boiling point ]
497.7±45.0 °C(Predicted) | [density ]
1.259±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: 2mg/mL, clear | [form ]
powder | [pka]
12.99±0.70(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Biological Activity]
AM-9074 is a potent activator of glucokinasewhich catalyzes the phosphorylation of glucose to glucose-6-phosphate. AM-9074 had an EC50 value of 160 nM with good solubilityoral bioavailability and acceptable clearance in rodentsand was shown to lower plasma glucose levels. |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|