ChemicalBook--->CAS DataBase List--->144313-54-2

144313-54-2

144313-54-2 Structure

144313-54-2 Structure
IdentificationBack Directory
[Name]

VALORPHIN
[CAS]

144313-54-2
[Synonyms]

VALORPHIN
Valorphin TFAsalt
VAL-VAL-TYR-PRO-TRP-THR-GLN
H-VAL-VAL-TYR-PRO-TRP-THR-GLN-OH
Valorphin H-Val-Val-Tyr-Pro-Trp-Thr-Gln-OH
L-Glutamine, L-valyl-L-valyl-L-tyrosyl-L-prolyl-L-tryptophyl-L-threonyl-
[Molecular Formula]

C44H61N9O11
[MDL Number]

MFCD00214653
[MOL File]

144313-54-2.mol
[Molecular Weight]

892.01
Chemical PropertiesBack Directory
[Boiling point ]

1364.0±65.0 °C(Predicted)
[density ]

1.330±0.06 g/cm3(Predicted)
[storage temp. ]

-15°C
[solubility ]

Soluble in DMSO
[pka]

3.21±0.10(Predicted)
[Sequence]

Val-Val-Tyr-Pro-Trp-Thr-Gln
Hazard InformationBack Directory
[Uses]

VV-Hemorphin-5 is a opioid peptide. Has been shown to have antitumor effects.
[in vivo]

Valorphin exhibits pronounced analgesic activity in mice, rats and rhesus monkeys via s.c, with ED50s of ≤5.2 mg/kg, but barely active after oral administration[1]. Valorphin (1 mg/kg) causes 42% of tumor growth inhibition in female BLRB mice bearing syngeneic mammary carcinoma cells[2].

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