ChemicalBook--->CAS DataBase List--->1443331-82-5

1443331-82-5

1443331-82-5 Structure

1443331-82-5 Structure
IdentificationBack Directory
[Name]

4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-(Methyl-d3)benzaMide
[CAS]

1443331-82-5
[Synonyms]

MDV 3100-d3
[2H3]-MDV 3100
[2H3]-Enzalutamide
4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-(methyl-d3)benzamide
4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-(Methyl-d3)benzaMide
[Molecular Formula]

C21H13D3F4N4O2S
[MDL Number]

MFCD29045174
[MOL File]

1443331-82-5.mol
[Molecular Weight]

467.454
Chemical PropertiesBack Directory
[Melting point ]

196-199°C
[storage temp. ]

Refrigerator
[solubility ]

Chloroform (Slightly), Ethyl Acetate (Slightly)
[form ]

Solid
[color ]

Off-White to Pale Yellow
Hazard InformationBack Directory
[Uses]

Labelled MDV 3100. MDV 3100 is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. MDV 3100 has also been shown to induce tumor cell apoptosis, and has no agonist activity. MDV 3100 is a candidate for the treatment of castration-resistant prostate cancer.
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