| Identification | Back Directory | [Name]
Dehydrodanshenol A | [CAS]
1444618-61-4 | [Synonyms]
Dehydrodanshenol A
Phenanthro[1,2-b]furan-11(10H)-one, 10-hydroxy-1,6-dimethyl-10-(2-oxopropyl)-, (10S)- | [Molecular Formula]
C21H18O4 | [MOL File]
1444618-61-4.mol | [Molecular Weight]
334.37 |
| Hazard Information | Back Directory | [Uses]
Dehydrodanshenol A is a non-competitive inhibitor of Protein tyrosine phosphatase 1B (PTP1B), with an IC50 value of 8.5 μM. Dehydrodanshenol A can be used in diabetes-related research[1]. | [IC 50]
PTP1B: 8.5 μM (IC50) | [References]
[1] Kim DH, et al. Characterization of the inhibitory activity of natural tanshinones from Salvia miltiorrhiza roots on protein tyrosine phosphatase 1B. Chem Biol Interact. 2017 Dec 25;278:65-73. DOI:10.1016/j.cbi.2017.10.013 |
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