ChemicalBook--->CAS DataBase List--->1444827-29-5

1444827-29-5

1444827-29-5 Structure

1444827-29-5 Structure
IdentificationBack Directory
[Name]

Aviptadil acetate
[CAS]

1444827-29-5
[Synonyms]

Vasoactive Intestinal Peptide acetate salt
[MOL File]

1444827-29-5.mol
[Molecular Weight]

3385.86
Chemical PropertiesBack Directory
[storage temp. ]

-20°C, protect from light
[solubility ]

DMSO: 100 mg/mL (29.53 mM)
[form ]

Solid
[color ]

White to off-white
[Water Solubility ]

Water: < 0.1 mg/mL (insoluble)
Hazard InformationBack Directory
[Uses]

Aviptadil acetate is an analog vasoactive intestinal polypeptide (VIP) with potent vasodilatory effects. Aviptadil acetate induces pulmonary vasodilation and inhibits vascular SMCs proliferation, platelet aggregation. Aviptadil acetate can be used for the research of pulmonary fibrosis, pulmonary arterial hypertension (PAH) and SARS-CoV-2 caused respiratory failure, et al[1].
[References]

[1] Intravenous Aviptadil for Critical COVID-19 With Respiratory Failure (COVID-AIV)
[2] Jian Hu, et al. Novel Targets of Drug Treatment for Pulmonary Hypertension. Am J Cardiovasc Drugs DOI:10.1007/s40256-015-0125-4
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