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1445592-86-8

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1445592-86-8 Structure

1445592-86-8 Structure
IdentificationBack Directory
[Name]

2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3S,5R)-
[CAS]

1445592-86-8
[Synonyms]

2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3S,5R)-
[Molecular Formula]

C11H18N2O3
[MOL File]

1445592-86-8.mol
[Molecular Weight]

226.27
Chemical PropertiesBack Directory
[Boiling point ]

388.9±21.0 °C(Predicted)
[density ]

1.228±0.06 g/cm3(Predicted)
[pka]

16.00±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

tert-Butyl (1R,3S,5R)-3-Carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate is an intermediate in the synthesis of ((2S,2R’,trans)-Saxagliptin (S143495), which is an impurity of Saxagliptin (S143500). Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4 (DPP-IV) developed for the treatment of type 2 diabetes.
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