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1445994-28-4

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1445994-28-4 Structure

1445994-28-4 Structure

Identification	Back Directory
[Name] 4-(5-amino-2-(2,4-difluorophenoxy)phenyl)-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one
[CAS] 1445994-28-4
[Synonyms] 4-(5-amino-2-(2,4-difluorophenoxy)phenyl)-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one 7H-Pyrrolo[2,3-c]pyridin-7-one, 4-[5-amino-2-(2,4-difluorophenoxy)phenyl]-1,6-dihydro-6-methyl-
[Molecular Formula] C20H15F2N3O2
[MOL File] 1445994-28-4.mol
[Molecular Weight] 367.35

Chemical Properties	Back Directory
[Boiling point ] 553.7±50.0 °C(Predicted)
[density ] 1.418±0.06 g/cm3(Predicted)
[pka] 14.88±0.40(Predicted)

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[Uses] PROTAC BRD4 ligand-3 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). PROTAC BRD4 ligand-3 can be used for synthesis PROTAC BRD4 Degrader-27 (HY-162875)[1].
[References] [1] Kong Y, et al. BRD4-specific PROTAC inhibits basal-like breast cancer partially through downregulating KLF5 expression. Oncogene. 2024 Sep;43(39):2914-2926. DOI:10.1038/s41388-024-03121-1

1445994-28-4 suppliers list

Company Name:	Wuxi AppTec
Telephone:	022-59987777 13552403979
Website:	www.labnetwork.com

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