| Identification | Back Directory | [Name]
Lubeluzole | [CAS]
144665-07-6 | [Synonyms]
R 87926
Prosynap
Lubeluzole dihydrochloride
1-Piperidineethanol, 4-(2-benzothiazolylmethylamino)-α-[(3,4-difluorophenoxy)methyl]-, (αS)-
(aS)-4-(2-Benzothiazolylmethylamino)-a-[(3,4-difluorophenoxy)methyl]-1-piperidineethanol dihydrochloride | [Molecular Formula]
C22H25F2N3O2S | [MDL Number]
MFCD00930465 | [MOL File]
144665-07-6.mol | [Molecular Weight]
433.521 |
| Chemical Properties | Back Directory | [Melting point ]
65.8° | [alpha ]
D20 +4.38° (c = 1 in methanol) | [storage temp. ]
2-8°C | [solubility ]
H2O: soluble2mg/mL, clear (warmed) | [form ]
powder | [color ]
white to beige | [Water Solubility ]
H2O: 2mg/mL, clear (warmed) | [InChI]
1S/C22H25F2N3O2S/c1-26(22-25-20-4-2-3-5-21(20)30-22)15-8-10-27(11-9-15)13-16(28)14-29-17-6-7-18(23)19(24)12-17/h2-7,12,15-16,28H,8-11,13-14H2,1H3/t16-/m0/s1 | [InChIKey]
OZFSWVOEXHGDES-INIZCTEOSA-N | [SMILES]
Fc1c(ccc(c1)OC[C@@H](O)CN2CCC(CC2)N(C)c3[s]c4c(n3)cccc4)F |
| Hazard Information | Back Directory | [Definition]
ChEBI: Lubeluzole is a member of benzothiazoles. | [Biological Activity]
Lubeluzole is an NMDA antagonist. Lubeluzole blocks glutamate releaseas well as sodium and calcium gated ion channels. Lubeluzole displays neuroprotective properties in ischemia models. |
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| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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