Identification | Back Directory | [Name]
lavendustin C6 | [CAS]
144676-04-0 | [Synonyms]
lavendustin C6 Lavendustin C-6,Lavendustin C6 Benzoic acid, 5-[[(2,5-dihydroxyphenyl)methyl]hexylamino]-2-hydroxy- | [Molecular Formula]
C20H25NO5 | [MOL File]
144676-04-0.mol | [Molecular Weight]
359.42 |
Hazard Information | Back Directory | [Uses]
Lavendustin C6 is a specific inhibitor of tyrosine kinase. Lavendustin C6 inhibits epidermal growth factor (EGF) receptor tyrosine kinase with an EC50 value of 0.05 μg/mL. Lavendustin C6 inhibits platelet-derived growth factor (PDGF)-induced inositol phosphate formation[1]. | [References]
[1] Imoto M, et al. Involvement of tyrosine kinase in growth factor-induced phospholipase C activation in NIH3T3 cells. Biochim Biophys Acta. 1993 Feb 24;1166(2-3):188-92. DOI:10.1016/0005-2760(93)90096-r |
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