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1446785-28-9

1446785-28-9 Structure

1446785-28-9 Structure
IdentificationBack Directory
[Name]

2-O-benzoyl-3-O-t-butyldiphenylsilyl-L-threonolactone
[CAS]

1446785-28-9
[Synonyms]

2-O-benzoyl-3-O-t-butyldiphenylsilyl-L-threonolactone
2-O-Benzoyl-3-O-tert-butyldiphenylsilyl-L-threonolactone
4-[(tert-Butyldiphenylsilyl)oxy]-2-oxo-3-tetrahydrofuryl (3R,4S)-Benzoate
2(3H)-Furanone, 3-(benzoyloxy)-4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]dihydro-, (3R,4S)-
[Molecular Formula]

C27H28O5Si
[MDL Number]

MFCD31707502
[MOL File]

1446785-28-9.mol
[Molecular Weight]

460.59
Chemical PropertiesBack Directory
[Boiling point ]

557.3±50.0 °C(Predicted)
[density ]

1.19±0.1 g/cm3(Predicted)
Hazard InformationBack Directory
[Uses]

2-O-Benzoyl-3-O-t-butyldiphenylsilyl-L-threono lactone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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