ChemicalBook--->CAS DataBase List--->144779-91-9

144779-91-9

144779-91-9 Structure

144779-91-9 Structure
IdentificationBack Directory
[Name]

(2S,3S)-3-[N-(Quinoxaline-2-carbonyl)-L-asparaginyl]amino-2-hydroxy-4- phenylbutanoyl-L-proline, tert-butylamide
[CAS]

144779-91-9
[Synonyms]

R87366
R-87366
R 87366
(2S,3S)-3-[N-(Quinoxaline-2-carbonyl)-L-asparaginyl]amino-2-hydroxy-4- phenylbutanoyl-L-proline, tert-butylamide
L-Prolinamide, N2-(2-quinoxalinylcarbonyl)-L-asparaginyl-(αS,βS)-β-amino-α-hydroxybenzenebutanoyl-N-(1,1-dimethylethyl)- (9CI)
[Molecular Formula]

C32H39N7O6
[MDL Number]

MFCD00953510
[MOL File]

144779-91-9.mol
[Molecular Weight]

617.7
Hazard InformationBack Directory
[Description]

R 87366 is a water-soluble HIV protease inhibitor.
[Uses]

R-87366 is a water-soluble human immunodeficiency virus (HIV) protease inhibitor. R-87366 has potent inhibitory for HIV protease with a Ki value of 11 nM. R-87366 can be used for the research of anti-human immunodeficiency virus (HIV)[1].
[References]

[1] T Komai, et al. In vitro and ex vivo anti-human immunodeficiency virus (HIV) activities of a new water-soluble HIV protease inhibitor, R-87366, containing (2S,3S)-3-amino-2-hydroxy-4-phenylbutanoic acid. Biol Pharm Bull. 1997 Feb;20(2):175-80. DOI:10.1248/bpb.20.175
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