ChemicalBook--->CAS DataBase List--->144887-95-6

144887-95-6

144887-95-6 Structure

144887-95-6 Structure
IdentificationBack Directory
[Name]

ASINEX-REAG BAS 03220609
[CAS]

144887-95-6
[Synonyms]

TIMTEC-BB SBB010706
ASINEX-REAG BAS 03220609
4-(2-chlorophenyl)butan-2-amine
Benzenepropanamine, 2-chloro-α-methyl-
3-(2-Chloro-phenyl)-1-methyl-propylamine
[Molecular Formula]

C10H14ClN
[MDL Number]

MFCD07391226
[MOL File]

144887-95-6.mol
[Molecular Weight]

183.68
Chemical PropertiesBack Directory
[Boiling point ]

263.2±23.0 °C(Predicted)
[density ]

1.072±0.06 g/cm3(Predicted)
[pka]

10.46±0.35(Predicted)
Safety DataBack Directory
[HazardClass ]

IRRITANT
Hazard InformationBack Directory
[Uses]

SK609 is a selective dopamine D3 receptor agonist with activity that improves dopamine and norepinephrine levels in the cerebral cortex. SK609 has been successfully used to suppress dyskinesias in Parkinson's disease models and alleviated muscle twitches induced by L-dopa. SK609 improved performance in sustained attention tasks by significantly reducing misses and false alarms. SK609 may provide an inhibitory option for suppressing movement and cognitive impairment in patients with Parkinson's disease[1].
[References]

[1] A novel dopamine D3R agonist SK609 with norepinephrine transporter inhibition promotes improvement in cognitive task performance in rodent and non-human primate models of Parkinson's disease DOI:10.1016/j.expneurol.2020.113514
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Company Name: AsInEx Ltd.  
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Company Name: TimTec Corporation  
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Website: www.timtec.net
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