| Identification | Back Directory | [Name]
3-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)propanoic acid | [CAS]
1450754-37-6 | [Synonyms]
Pr-DiAz-COOH
Alkyne-Diazirine-COOH
3-(3-(BUT-3-YN-1-YL)-3H-DIAZIRIN-3-YL)
3-(3-Butyn-1-yl)-3H-diazirine-3-propanoic acid
3H-Diazirine-3-propanoic acid, 3-(3-butyn-1-yl)-
3-?(3-?(But-?3-?yn-?1-?yl)?-?3H-?diazirin-?3-?yl)?
3-[3-(3-Butyn-1-yl)-3H-diazirin-3-yl]propanoic Acid
3-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)propanoic acid | [EINECS(EC#)]
817-943-6 | [Molecular Formula]
C8H10N2O2 | [MDL Number]
MFCD31433997 | [MOL File]
1450754-37-6.mol | [Molecular Weight]
166.18 |
| Chemical Properties | Back Directory | [Boiling point ]
287.2±36.0 °C(Predicted) | [density ]
1.17±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | [form ]
Solid-Liquid Mixture | [pka]
4.55±0.10(Predicted) | [color ]
Off-white to light yellow | [InChI]
InChI=1S/C8H10N2O2/c1-2-3-5-8(9-10-8)6-4-7(11)12/h1H,3-6H2,(H,11,12) | [InChIKey]
JRNSKSYASHYNCM-UHFFFAOYSA-N | [SMILES]
N1C(CCC#C)(CCC(O)=O)N=1 |
| Hazard Information | Back Directory | [Uses]
Used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments. | [reaction suitability]
reaction type: click chemistry |
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