ChemicalBook--->CAS DataBase List--->1451362-51-8

1451362-51-8

1451362-51-8 Structure

1451362-51-8 Structure
IdentificationBack Directory
[Name]

CbzNH-PEG4-CH2COOH
[CAS]

1451362-51-8
[Synonyms]

CbzNH-PEG4-CH2COOH
3-Oxo-1-phenyl-2,7,10,13,16-pentaoxa-4-azaoctadecan-18-oic acid
5,8,11,14-Tetraoxa-2-azahexadecanedioic acid, 1-(phenylmethyl) ester
[Molecular Formula]

C18H27NO8
[MDL Number]

MFCD30528569
[MOL File]

1451362-51-8.mol
[Molecular Weight]

385.41
Chemical PropertiesBack Directory
[storage temp. ]

Store at 0-8 °C
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319
[Precautionary statements ]

P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard InformationBack Directory
[Description]

CbzNH-PEG4-CH2COOH is a PEG linker containing an carboxylic acid (CO2H) group and a benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The terminal carboxylic acid is reactive with primary amine groups in the presence of activators (e.g. EDC, or HATU) forming a stable amide bond. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
[Uses]

CbzNH-PEG4-CH2COOH is a PEG linker containing an carboxylic acid (CO2H) group and a benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The terminal carboxylic acid is reactive with primary amine groups in the presence of activators (e.g. HATU) forming a stable amide bond. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
Spectrum DetailBack Directory
[Spectrum Detail]

CbzNH-PEG4-CH2COOH(1451362-51-8)1HNMR
CbzNH-PEG4-CH2COOH(1451362-51-8)13CNMR
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