| Identification | Back Directory | [Name]
1-hydroxyoxaunomycin | [CAS]
145165-10-2 | [Synonyms]
1-hydroxyoxaunomycin
5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-ethyl-7,8,9,10-tetrahydro-1,4,6,7,8,11-hexahydroxy-, [7R-(7α,8β,10β)]-
5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-ethyl-7,8,9,10-tetrahydro-1,4,6,7,8,11-hexahydroxy-, [7R-(7α,8β,10β)]- (9CI) | [Molecular Formula]
C26H29NO11 | [MOL File]
145165-10-2.mol | [Molecular Weight]
531.51 |
| Hazard Information | Back Directory | [Uses]
1-Hydroxyoxaunomycin is an antibiotic. 1-Hydroxyoxaunomycin inhibits U210 cell growth, DNA synthesis and RNA synthesis with IC50 of 0.0005 μg/mL, 1.00 μg/mL and 0.76 μg/mL respectively[1]. | [References]
[1] A Yoshimoto, et al. Production of new anthracycline antibiotics 1-hydroxy-oxaunomycin and 6-deoxyoxaunomycin by limited biosynthetic conversion using a daunorubicin-negative mutant. J Antibiot (Tokyo). 1992 Oct;45(10):1609-17. |
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