| Identification | Back Directory | [Name]
H-MET-SER-OH | [CAS]
14517-43-2 | [Synonyms]
MET-SER
L-MET-SER
Met-Ser-OH
H-MET-SER-OH
L-Met-L-Ser-OH
Methionylserine
L-METHIONYL-L-SERINE
L-Serine, L-methionyl-
N-L-Methionyl-L-serine
76: PN: WO2012021247 SEQID: 87 claimed protein
(S)-2-((S)-2-Amino-4-(methylthio)butanamido)-3-hydroxypropanoic acid | [Molecular Formula]
C8H16N2O4S | [MDL Number]
MFCD00037246 | [MOL File]
14517-43-2.mol | [Molecular Weight]
236.29 |
| Hazard Information | Back Directory | [Uses]
Methionylserine (H-MET-SER-OH) is a methionine- and serine-containing dipeptide. Methionylserine binds to and translocation via intestinal di/tri-peptide transporter 1 (hPEPT1) with a Km value of 0.2 mM. Methionylserine inhibits ACE enzyme activity. Methionylserine can be used in the research of hypension[1][2]. | [Definition]
ChEBI: Met-Ser is a dipeptide composed of L-methionine and L-serine joined by a peptide linkage. It has a role as a metabolite. It is functionally related to a L-methionine and a L-serine. | [References]
[1] Diana H?jmark Omkvist, et al. Affinity and translocation relationships via hPEPT1 of H-X aa-Ser-OH dipeptides: evaluation of H-Phe-Ser-OH as a pro-moiety for ibuprofen and benzoic acid prodrugs. Eur J Pharm Biopharm. 2011 Feb;77(2):327-31. DOI:10.1016/j.ejpb.2010.12.009
[2] Pan Wuguang, et al. Application of sulfur dipeptide for preparing antihypertensive drug or health care product. Patent WO2019006954. |
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| Company Name: |
Ontores Biotech
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| Tel: |
0571-88760729 18072970094 |
| Website: |
www.ontoresinc.cn |
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