ChemicalBook--->CAS DataBase List--->145194-26-9

145194-26-9

145194-26-9 Structure

145194-26-9 Structure
IdentificationBack Directory
[Name]

SENDIDE
[CAS]

145194-26-9
[Synonyms]

SENDIDE
(tyr6,D-phe7
TYR-D-PHE-PHE-D-HIS-LEU-MET-NH2
H-TYR-D-PHE-PHE-D-HIS-LEU-MET-NH2
(TYR6,D-PHE7,D-HIS9)-SUBSTANCE P (6-11)
[TYR6,D-PHE7,D-HIS9]-SUBSTANCE P, FRAGMENT 6-11
(Tyr6,D-Phe7,D-His9)-Substance P (6-11), Sendide
Substance P, fragment 6-11, [Tyr6, D-Phe7, D-His9]
L-Methioninamide, L-tyrosyl-D-phenylalanyl-L-phenylalanyl-D-histidyl-L-leucyl-
[Molecular Formula]

C44H57N9O7S
[MDL Number]

MFCD00214682
[MOL File]

145194-26-9.mol
[Molecular Weight]

856.04
Chemical PropertiesBack Directory
[RTECS ]

WM2780700
[storage temp. ]

-15°C
[form ]

Solid
[Sequence]

Tyr-{d-Phe}-Phe-{d-His}-Leu-Met-NH2
Hazard InformationBack Directory
[Uses]

[Tyr6,D-Phe7,D-His9]-Substance P (6-11) is a tachykinin NK1 receptor antagonist that antagonizes Histamine (HY-B1204) induced hyperalgesia[1].
[References]

[1] Sakurada, et al. "Possible involvement of tachykinin NK1 and NMDA receptors in histamine-induced hyperalgesia in mice." European journal of pharmacology 434.1-2 (2002): 29-34. DOI:10.1016/s0014-2999(01)01523-0
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