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145257-03-0

145257-03-0 Structure

145257-03-0 Structure
IdentificationBack Directory
[Name]

Guanylin, rat, Mouse
[CAS]

145257-03-0
[Synonyms]

(1R,4S,7S,10S,13S,16R,21R,27S,34R,37S,40S)-34-[[(2S,3R)-2-[[(2S)-4-amino-4-oxo-2-[[(2S)-pyrrolidine-2-carbonyl]amino]butanoyl]amino]-3-hydroxybutanoyl]amino]-40-[(2S)-butan-2-yl]-37-(2-carboxyethyl)-27-[(1R)-1-hydroxyethyl]-10-[(4-hydroxyphenyl)methyl]-4,7,13-trimethyl-3,6,9,12,15,23,26,29,35,38,41-undecaoxo-18,19,31,32-tetrathia-2,5,8,11,14,22,25,28,36,39,42-undecazabicyclo[14.13.13]dotetracontane-21-carboxylic acid
[Molecular Formula]

Ni
[MOL File]

145257-03-0.mol
[Molecular Weight]

58.6934
Chemical PropertiesBack Directory
[Sequence]

Pro-Asn-Thr-Cys-Glu-Ile-Cys-Ala-Tyr-Ala-Ala-Cys-Thr-Gly-Cys (Disulfide bonds: Cys4-Cys12, Cys7-Cys15)
Hazard InformationBack Directory
[Uses]

Guanylin (mouse, rat), a petide, is composed of 15 amino acids. Guanylin (mouse, rat) is an activator of intestinal guanylate cyclase. Guanylin (mouse, rat) can be used for the research of diarrhea[1].
[References]

[1] Currie MG, et al. Guanylin: an endogenous activator of intestinal guanylate cyclase. Proc Natl Acad Sci U S A. 1992 Feb 1;89(3):947-51. DOI:10.1073/pnas.89.3.947
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