| Identification | Back Directory | [Name]
Bicyclo[3.2.1]oct-3-en-2-one, 7-(1,3-benzodioxol-5-yl)-8-hydroxy-5-methoxy-6-methyl-3-(2-propen-1-yl)-, (1S,5R,6R,7R,8R)- | [CAS]
145701-13-9 | [Synonyms]
Kadsurenin B
Bicyclo[3.2.1]oct-3-en-2-one, 7-(1,3-benzodioxol-5-yl)-8-hydroxy-5-methoxy-6-methyl-3-(2-propen-1-yl)-, (1S,5R,6R,7R,8R)- | [Molecular Formula]
C20H22O5 | [MOL File]
145701-13-9.mol | [Molecular Weight]
342.39 |
| Hazard Information | Back Directory | [Uses]
Kadsurenin B is a PAF (platelet-activating factor) antagonist with neuroprotective activity. Kadsurenin B has a wide range of pharmacological research potential, such as antibacterial, anti-inflammatory, neuroprotective, antioxidant, antiplatelet aggregation, cytotoxic, antiparasitic, etc[1][2]. | [References]
[1] Ma Y, et al. Studies on PAF antagonistic bicyclo(3,2,1) octanoid neolignans from Piper kadsura. Yao Xue Xue Bao. 1993;28(3):207-11. PMID:8368081
[2] Fan D, et al. Lignans from the genus Piper L. and their pharmacological activities: An updated review. Fitoterapia. 2023 Mar;165:105403. DOI:10.1016/j.fitote.2022.105403 |
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