ChemicalBook--->CAS DataBase List--->145854-59-7

145854-59-7

145854-59-7 Structure

145854-59-7 Structure
IdentificationBack Directory
[Name]

MAS 7
[CAS]

145854-59-7
[Synonyms]

MAS 7
MASTOPARAN 7
INLKALAALAKALL-NH2
Mastoparan-7, ≥97% (HPLC)
MASTOPARAN 7 SYNTHETIC >98%
mastoparan from polistes jadwagae
MAS 7 - CAS 145854-59-7 - Calbiochem
Mastoparan-7 >=97% (HPLC), lyophilized powder
19: PN: WO2010069074 SEQID: 17 claimed protein
ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-ALA-LEU-LEU-NH2
H-ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-ALA-LEU-LEU-NH2
L-Leucinamide,L-isoleucyl-L-asparaginyl-L-leucyl-L-lysyl-L-alanyl-L-leucyl-L-alanyl-L-alanyl-L-leucyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-
[Molecular Formula]

C67H124N18O15
[MDL Number]

MFCD00144726
[MOL File]

145854-59-7.mol
[Molecular Weight]

1421.81
Chemical PropertiesBack Directory
[Boiling point ]

1649.9±65.0 °C(Predicted)
[density ]

1.154±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C
[form ]

lyophilized powder
[pka]

13.43±0.46(Predicted)
[color ]

White to off-white
[Water Solubility ]

water: 5mg/mL
[Sequence]

Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Ala-Leu-Leu-NH2
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS07,GHS08
[Signal word ]

Danger
[Hazard statements ]

H317-H334
[Precautionary statements ]

P261-P280-P342+P311
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Mastoparan-7 has been used to study mastoparan-stimulated nucleotide binding to G proteins.
[General Description]

Mastoparan-7 is an analog of the mastoparan peptide. It is present in the venom of Vespula lewisii. It was originally isolated from wasp venom.
[Biochem/physiol Actions]

Mastoparan-7 (Mas-7) stimulates the G protein subunit Gαo/i by its mode of action (to bind to the plasma membrane). It possesses antiviral activity and is associated with histamine release from mast cells. It is also involved in the induction of potent mitochondrial permeability and tumor cell cytotoxicity.
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