| Identification | Back Directory | [Name]
GJ-103 sodium salt | [CAS]
1459687-96-7 | [Synonyms]
GJ 103;GJ-103
GJ-103 sodium
GJ-103 sodium salt | [Molecular Formula]
C16H15N4NaO3S | [MDL Number]
MFCD30738009 | [MOL File]
1459687-96-7.mol | [Molecular Weight]
366.37 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF:30.0(Max Conc. mg/mL);82.34(Max Conc. mM)
DMSO:40.0(Max Conc. mg/mL);109.78(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:2):0.33(Max Conc. mg/mL);0.91(Max Conc. mM) | [form ]
A crystalline solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
GJ103 sodium salt is an active analog of the read-through compound GJ072. Chemical-induced read through of premature stop codons might be exploited as a potential treatment strategy for genetic disorders caused by nonsense mutations. | [Uses]
GJ103 sodium is a read-through compound that can induce read through of premature stop codons. GJ103 sodium has potential for the research of genetic disorders caused by nonsense mutations[1]. | [target]
GJ103 sodium salt is an active analog of the read-through compound GJ072. | [References]
[1] Du L, et al. A new series of small molecular weight compounds induce read through of all three types of nonsense mutations in the ATM gene. Mol Ther. 2013 Sep;21(9):1653-60. DOI:10.1038/mt.2013.150 |
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
ChemeGen
|
| Tel: |
18818260767 |
| Website: |
https://www.chemegen.com |
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