| Identification | Back Directory | [Name]
6,6-dimethyl-3-(4-methylbenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine | [CAS]
1461715-47-8 | [Synonyms]
GLP-1 Receptor modulator 1
6,6-dimethyl-3-(4-methylbenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine
Methanone, (2-amino-4,5,6,7-tetrahydro-6,6-dimethylbenzo[b]thien-3-yl)(4-methylphenyl)- | [Molecular Formula]
C18H21NOS | [MOL File]
1461715-47-8.mol | [Molecular Weight]
299.43 |
| Chemical Properties | Back Directory | [Boiling point ]
503.8±50.0 °C(Predicted) | [density ]
1.148±0.06 g/cm3(Predicted) | [solubility ]
DMSO: Sparingly soluble: 1-10 mg/ml
Ethanol: Slightly soluble: 0.1-1 mg/ml | [pka]
-0.86±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
GLP-1 Receptor modulator 1 (Compound 7) is a potent GLP-1 receptor positive allosteric modulator. GLP-1 Receptor modulator 1 can be used for the research of obesity and type 2 diabetes[1]. | [References]
[1] Campbell JA, et al. Synthesis and biological studies of 2-aminothiophene derivatives as positive allosteric modulators of glucagon-like peptide 1 receptor. Bioorg Med Chem. 2024 Sep 1;111:117864. DOI:10.1016/j.bmc.2024.117864 |
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