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146196-08-9

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146196-08-9 Structure

146196-08-9 Structure
IdentificationBack Directory
[Name]

2-Chloro-N6-methyl-2’-deoxyadenosine
[CAS]

146196-08-9
[Synonyms]

2-Chloro-N6-methyl-2’-deoxyadenosine
Adenosine, 2-chloro-2'-deoxy-N-methyl-
[Molecular Formula]

C11H14ClN5O3
[MDL Number]

MFCD28343296
[MOL File]

146196-08-9.mol
[Molecular Weight]

299.71
Chemical PropertiesBack Directory
[Boiling point ]

580.9±60.0 °C(Predicted)
[density ]

1.83±0.1 g/cm3(Predicted)
[pka]

13.76±0.60(Predicted)
Hazard InformationBack Directory
[Uses]

2-Chloro-N6-methyl-2’-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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