Identification | Back Directory | [Name]
D-?Ribitol, 1,?4-?anhydro-?5-?O-?[bis(4-?methoxyphenyl)?phenylmethyl]?-?2-?O-?methyl-?, 3-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | [CAS]
1470023-72-3 | [Synonyms]
DMT-2'-OMe-D-Ribitol phosphoramidite (2R,3S,4S)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite D-Ribitol, 1,4-anhydro-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-O-methyl-, 3-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] (ACI) D-?Ribitol, 1,?4-?anhydro-?5-?O-?[bis(4-?methoxyphenyl)?phenylmethyl]?-?2-?O-?methyl-?, 3-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | [Molecular Formula]
C36H47N2O7P | [MOL File]
1470023-72-3.mol | [Molecular Weight]
650.75 |
Hazard Information | Back Directory | [Uses]
DMT-2'-OMe-D-Ribitol phosphoramidite (compound 9) is an abasic phosphoramidite monomer that can be used to introduce the abasic group Y34 into oligonucleotides[1]. | [References]
[1] Liu J, et al. RNA duplexes with abasic substitutions are potent and allele-selective inhibitors of huntingtin and ataxin-3 expression. Nucleic Acids Res. 2013 Oct;41(18):8788-801. DOI:10.1093/nar/gkt594 |
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