| Identification | Back Directory | [Name]
2,6-Piperidinedione, 3-[(3-aminophenyl)amino]- | [CAS]
1472731-41-1 | [Synonyms]
E3 ligase Ligand 56
3-((3-Aminophenyl)amino)piperidine-2,6-dione
2,6-Piperidinedione, 3-[(3-aminophenyl)amino]- | [Molecular Formula]
C11H13N3O2 | [MOL File]
1472731-41-1.mol | [Molecular Weight]
219.24 |
| Hazard Information | Back Directory | [Uses]
E3 ligase Ligand 56 is the ligand for E3 ligase Cereblon and can be used for syntheisis of PROTAC CDK9 degrader-11 (HY-170978)[1]. | [References]
[1] Wang Y, et al., Identification of a Potent and Selective CDK9 Degrader as a Targeted Therapeutic Option for the Treatment of Small-Cell Lung Cancer. J Med Chem. 2025 Feb 13;68(3):2528-2550. DOI:10.1021/acs.jmedchem.4c01621 |
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