ChemicalBook--->CAS DataBase List--->147362-57-0

147362-57-0

147362-57-0 Structure

147362-57-0 Structure
IdentificationBack Directory
[Name]

Loviride
[CAS]

147362-57-0
[Synonyms]

Loviride
LOVIRIDE (R 89439)
2-(2-acetyl-5-methylanilino)-2-(2,6-dichlorophenyl)acetamide
Benzeneacetamide, α-[(2-acetyl-5-methylphenyl)amino]-2,6-dichloro-
[Molecular Formula]

C17H16Cl2N2O2
[MOL File]

147362-57-0.mol
[Molecular Weight]

351.23
Chemical PropertiesBack Directory
[Melting point ]

226.3 °C
[Boiling point ]

550.3±50.0 °C(Predicted)
[density ]

1.44 g/cm3
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

15.01±0.50(Predicted)
[color ]

Light yellow to yellow
[InChI]

1S/C17H16Cl2N2O2/c1-9-6-7-11(10(2)22)14(8-9)21-16(17(20)23)15-12(18)4-3-5-13(15)19/h3-8,16,21H,1-2H3,(H2,20,23)
[InChIKey]

CJPLEFFCVDQQFZ-UHFFFAOYSA-N
[SMILES]

Clc1c(c(ccc1)Cl)C(Nc2c(ccc(c2)C)C(=O)C)C(=O)N
Safety DataBack Directory
[WGK Germany ]

WGK 3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

Antiviral.
[Biological Activity]

Loviride is an orally availablepotent and selective inhibitor of reverse transcriptase HIV-1 th at inhibits HIV replication in cells. Alsoloviride inhibits replication of HIV-2 and SIV in cells.
[IC 50]

HIV-1; HIV-2
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