| Identification | Back Directory | [Name]
3-(Boc-aMino)-3-Methylpyrrolidine | [CAS]
147459-52-7 | [Synonyms]
3-(Boc-aMino)-3-Methylpyr...
3-(Boc-aMino)-3-Methylpyrrolidine
tert-Butyl (3-Methylpyrrolidin-3-yl)carbaMate
tert-butyl N-(3-methylpyrrolidin-3-yl)carbamate
(3-Methyl-pyrrolidin-3-yl)-carbamic acid tert-butyl ester
Carbamic acid, N-(3-methyl-3-pyrrolidinyl)-, 1,1-dimethylethyl ester | [Molecular Formula]
C10H20N2O2 | [MDL Number]
MFCD09951966 | [MOL File]
147459-52-7.mol | [Molecular Weight]
200.28 |
| Chemical Properties | Back Directory | [Boiling point ]
289.8±29.0 °C(Predicted) | [density ]
1.02±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [pka]
12.58±0.20(Predicted) | [Appearance]
White to off-white Solid | [InChI]
InChI=1S/C10H20N2O2/c1-9(2,3)14-8(13)12-10(4)5-6-11-7-10/h11H,5-7H2,1-4H3,(H,12,13) | [InChIKey]
DIQWSFWWYVRXRO-UHFFFAOYSA-N | [SMILES]
C(OC(C)(C)C)(=O)NC1(C)CCNC1 |
| Hazard Information | Back Directory | [Synthesis]
Step E: A solution of benzyl 3-(tert-butoxycarbonylamino)-3-methylpyrrolidine-1-carboxylate (2.00 g, 5.98 mmol) and 10% Pd/C (0.32 g, 0.30 mmol) in methanol (20 mL) was reacted under stirring conditions for 1 hour in a hydrogen atmosphere. Upon completion of the reaction, the catalyst was removed by filtration and washed with methanol. The filtrate was concentrated to afford tert-butyl (3-methylpyrrolidin-3-yl)carbamate (1.15 g, 96% yield) in solid form. | [References]
[1] Patent: WO2009/140320, 2009, A1. Location in patent: Page/Page column 74-75 |
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