| Identification | Back Directory | [Name]
AC-VAD-CHO | [CAS]
147837-52-3 | [Synonyms]
AC-VAD-CHO
Ac-Val-Ala-Asp-al
AC-VAL-ALA-ASP-CHO
CASPASE INHIBITOR II
AC-VAD-CHO USP/EP/BP
N-ACETYL-VAL-ALA-ASP-AL
AC-VAL-ALA-ASP-ALDEHYDE
N-acetyl-Val-Ala-Asp-Ala
CASPASE INHIBITOR II CHO
Acetyl-valyl-alanyl-aspartal
N-Acetyl-Val-Ala-Asp-al >=98% (TLC)
N-Acetyl-Val-Ala-Asp-al (AC-VAD-CHO)
AC-VAL-ALA-ASP-ALDEHYDE (PSEUDO ACID)
N-Acetyl-Val-Ala-Asp-al (AC-VAD-CHO), ≥98%
L-Alaninamide, N-acetyl-L-valyl-N-[(1S)-2-carboxy-1-formylethyl]-
(S)-3-((S)-2-((S)-2-Acetamido-3-methylbutanamido)propanamido)-4-oxobutanoic acid | [Molecular Formula]
C14H23N3O6 | [MDL Number]
MFCD00672421 | [MOL File]
147837-52-3.mol | [Molecular Weight]
329.35 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C | [solubility ]
DMSO: 150mg/mL | [form ]
White solid | [color ]
white | [Sequence]
Ac-Val-Ala-Asp-CHO | [InChI]
1S/C14H23N3O6/c1-7(2)12(16-9(4)19)14(23)15-8(3)13(22)17-10(6-18)5-11(20)21/h6-8,10,12H,5H2,1-4H3,(H,15,23)(H,16,19)(H,17,22)(H,20,21)/t8-,10-,12-/m0/s1 | [InChIKey]
BGFYQRSQECIBIB-PEXQALLHSA-N | [SMILES]
CC(C)[C@H](NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C=O |
| Hazard Information | Back Directory | [Uses]
Ac-VAD-CHO (Ac-Val-Ala-Asp-CHO) is a pan-caspase inhibitor. Ac-VAD-CHO inhibits dissipation of MMP and cytochrome c release in hypoxia-exposed cells[1]. | [Biological Activity]
Cell permeable: no''Primary Target
pan-caspase''Product does not compete with ATP.''Reversible: yes | [References]
[1] Jee-Youn Kim, et al. ROS-dependent caspase-9 activation in hypoxic cell death. FEBS Lett. 2003 Aug 14;549(1-3):94-8. DOI:10.1016/s0014-5793(03)00795-6 |
|
| Company Name: |
Alabiotech Inc.
|
| Tel: |
001-619-354-5251 |
| Website: |
www.alabiotech-e.com |
|