| Identification | Back Directory | [Name]
7-METHYL-JUGLONE | [CAS]
14787-38-3 | [Synonyms]
Nsc624625
NSC208733
NSC-208733
NSC 208733
Aids108047
Aids-108047
Ramentaceone
7-METHYL-JUGLONE
5-Hydroxy-7-methyl-1,4-naphthoquinone
6-Methyl-8-hydroxy-1,4-naphthoquinone
7-Methyl-5-hydroxy-1,4-naphthoquinone
5-Hydroxy-7-methyll-,1,4-naphtoquinone
7-Methyl-5-hydroxynaphthalene-1,4-dione
5-hydroxy-7-methyl-1,4-Naphthalenedione
5-hydroxy-7-methylnaphthalene-1,4-dione
1,4-Naphthalenedione, 5-hydroxy-7-methyl-
5-hydroxy-7-Methyl-1,4-dihydronaphthalene-1,4-dione
5-Hydroxy-7-methyl-2,3-dihydronaphthal-ene-1,4-dione | [Molecular Formula]
C11H8O3 | [MDL Number]
MFCD01712152 | [MOL File]
14787-38-3.mol | [Molecular Weight]
188.181 |
| Chemical Properties | Back Directory | [Melting point ]
125.5-126.5 °C | [Boiling point ]
427.2±45.0 °C(Predicted) | [density ]
1.44 g/cm3 | [storage temp. ]
2-8°C | [pka]
6.66±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
Ramentaceone (7-Methyljuglon), a naphthoquinone that can be isolated from Drosera sp., inhibits PI3K activity. Ramentaceone (7-Methyljuglon) reduces the expression of the PI3K protein and inhibits the phosphorylation of the Akt protein in breast cancer cells. Ramentaceone (7-Methyljuglon) induces apoptosis[1]. | [Definition]
ChEBI: Ramentaceone is a hydroxy-1,4-naphthoquinone. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 49, p. 3766, 1984 DOI: 10.1021/jo00194a017 | [References]
[1] Anna Kawiak, et al. Ramentaceone, a Naphthoquinone Derived from Drosera sp., Induces Apoptosis by Suppressing PI3K/Akt Signaling in Breast Cancer Cells. PLoS One. 2016 Feb 3;11(2):e0147718. DOI:10.1371/journal.pone.0147718 |
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NovoChemy Ltd.
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021-31261262/ 49 (0)17662837245 |
| Website: |
www.novochemy.com |
| Company Name: |
Tcichem, Inc.
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13918644899 |
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www.chemicalbook.com/ShowSupplierProductsList19113/0_EN.htm |
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