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148077-13-8

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148077-13-8 Structure

148077-13-8 Structure
IdentificationBack Directory
[Name]

lincophenicol
[CAS]

148077-13-8
[Synonyms]

lincophenicol
2-Pyrrolidinecarboxamide, N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-1-methyl-4-propyl-, [2S-[2α(1S*,2S*),4β]]- (9CI)
[Molecular Formula]

C18H27N3O5
[MOL File]

148077-13-8.mol
[Molecular Weight]

365.43
Chemical PropertiesBack Directory
[Boiling point ]

616.5±55.0 °C(Predicted)
[density ]

1.236±0.06 g/cm3(Predicted)
[pka]

12.68±0.20(Predicted)
Hazard InformationBack Directory
[Description]

Lincophenicol is an inhibitor of Escherichia coli ribosomal peptidyltransferase-catalyzed puromycin reaction.
[Uses]

Lincophenicol is a hybrid antibiotic that has the activity of inhibiting the puromycin reaction catalyzed by Escherichia coli ribosomal peptidyl transferase and also inhibits the binding of specific compounds to the Escherichia coli ribosome.
[References]

[1] Hybrids of antibiotics inhibiting protein synthesis. Synthesis and biological activity
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