| Identification | Back Directory | [Name]
HC 067047 Hydrochloride | [CAS]
1481646-76-7 | [Synonyms]
HC 067047 Hydrochloride
HC067047 Hydrochloride(883031-03-6 free base)
HC067047 Hydrochloride(883031 03 6 free base),HC-067047 Hydrochloride(883031-03-6 free base),HC067047 Hydrochloride(883031036 free base) | [Molecular Formula]
C26H29ClF3N3O2 | [MOL File]
1481646-76-7.mol | [Molecular Weight]
507.98 |
| Hazard Information | Back Directory | [Uses]
HC 067047 is a transient potential vanilloid 4 receptor antagonist, reducing scarring and inflammation in pulmonary disease. Also used in the treatment of hypertension. | [in vivo]
HC-067047 hydrochloride (0-50 mg/kg; intraperitoneal injection; for 30 minutes; cyclophosphamide-treated WT and Trpv4-/- mice, and naive WT mice) treatment increases functional bladder capacity and reduces micturition frequency in WT mice with cystitis. HC-067047 do not affect bladder function in Trpv4-/- mice[1]. |
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