| Identification | Back Directory | [Name]
L-Asparagine, N2-[[(3R,3aS,6aR,9aR,9bS)-dodecahydro-6,9-bis(methylene)-2-oxoazuleno[4,5-b]furan-3-yl]methyl]- | [CAS]
148245-83-4 | [Synonyms]
L-Asparagine, N2-[[(3R,3aS,6aR,9aR,9bS)-dodecahydro-6,9-bis(methylene)-2-oxoazuleno[4,5-b]furan-3-yl]methyl]- | [Molecular Formula]
C19H26N2O5 | [MOL File]
148245-83-4.mol | [Molecular Weight]
362.42 |
| Hazard Information | Back Directory | [Description]
Saussureamine C is an inhibitor of H274Y and N294S mutants. | [Uses]
Saussureamine C shows gastroprotective effect on acidified ethanol-induced gastric mucosal lesions in rats. Saussureamine C inhibits H274Y and N294S mutants and can be used for research of influenza virus infection. Saussureamine C can be isolated from the dried roots of Saussurea lappa Clarke[1][2]. | [References]
[1] Yoshikawa M, et al. Saussureamines A, B, C, D, and E, new anti-ulcer principles from Chinese Saussureae Radix. Chem Pharm Bull (Tokyo). 1993 Jan;41(1):214-6. DOI:10.1248/cpb.41.214
[2] Tou WI, et al. Residue-based design of small molecule inhibitor for H1N1, H5N1 and H7N1 mutants. J Mol Model. 2016 Jan;22(1):4. DOI:10.1007/s00894-015-2875-y |
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