| Identification | Back Directory | [Name]
Ethanone, 1-[4,5-dihydro-3-(4-hydroxyphenyl)-5-(4-methoxyphenyl)-1H-pyrazol-1-yl]- | [CAS]
148404-10-8 | [Synonyms]
Ethanone, 1-[4,5-dihydro-3-(4-hydroxyphenyl)-5-(4-methoxyphenyl)-1H-pyrazol-1-yl]- | [Molecular Formula]
C18H18N2O3 | [MOL File]
148404-10-8.mol | [Molecular Weight]
310.35 |
| Chemical Properties | Back Directory | [Melting point ]
217-218 °C | [Boiling point ]
494.7±55.0 °C(Predicted) | [density ]
1.23±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
9.92±0.30(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
α Amylase-IN-1 (Compound 11) is an α-Amylase inhibitor with an IC50 value of 0.5509 μM. α Amylase-IN-1 has antioxidant activity with an IC50 value of 53.49 μM for scavenging DPPH free radicals. IC50 can be used in the study of diabetes and oxidative stress-related diseases.[1] | [References]
[1] Ali A, et al. Dihydropyrazole Derivatives Act as Potent α-Amylase Inhibitors and Free Radical Scavengers: Synthesis, Bioactivity Evaluation, Structure-Activity Relationship, ADMET, and Molecular Docking Studies. ACS Omega. 2023 Jun 2;8(23):20412-20422. DOI:10.1021/acsomega.3c00529 |
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