ChemicalBook--->CAS DataBase List--->148702-58-3

148702-58-3

148702-58-3 Structure

148702-58-3 Structure
IdentificationBack Directory
[Name]

SB 204070
[CAS]

148702-58-3
[Synonyms]

SB 204070
SB 204070 HCl
SB-204070 hydrochloride solid, >=97% (HPLC)
(1-Butyl-4-piperidinyl)methyl-8-amino-7-chloro-1,4-benzodioxane-5-carboxylate
(1-butyl-4-piperidinyl)methyl-8-amino-7-chloro-1,4-benzodioxane-5-carboxylate hydrochloride
(1-Butylpiperidin-4-yl)methyl 8-amino-7-chloro-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate
1,4-Benzodioxin-5-carboxylic acid, 8-amino-7-chloro-2,3-dihydro-, (1-butyl-4-piperidinyl)methyl ester
[Molecular Formula]

C19H27ClN2O4
[MDL Number]

MFCD03453014
[MOL File]

148702-58-3.mol
[Molecular Weight]

382.88
Chemical PropertiesBack Directory
[Melting point ]

243-245 °C(lit.)
[solubility ]

H2O: 20 mg/mL with heating
[form ]

solid
[Water Solubility ]

H2O: 20mg/mL (with heating)
[InChI]

1S/C19H27ClN2O4.ClH/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18;/h11,13H,2-10,12,21H2,1H3;1H
[InChIKey]

YEQGKAOSYSXEPU-UHFFFAOYSA-N
[SMILES]

Cl[H].CCCCN1CCC(CC1)COC(=O)c2cc(Cl)c(N)c3OCCOc23
Safety DataBack Directory
[WGK Germany ]

3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

SB 204070 is a selective 5-HT4 antagonist.
[Biological Activity]

SB-204070 is a highly potent and specific antagonist of 4-HT4 receptor. It inhibits cholinergic and noncholinergic transmission and blocks the contractions of proximal colon in guinea pigs and relaxation of human colon circular smooth muscle.''Selective 5-HT4 serotonin receptor antagonist.
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