ChemicalBook--->CAS DataBase List--->148766-37-4

148766-37-4

148766-37-4 Structure

148766-37-4 Structure
IdentificationBack Directory
[Name]

(R)-2-METHYLCYSTEINE HYDROCHLORIDE
[CAS]

148766-37-4
[Synonyms]

α-Me-Cys-OH·HCl
H-alpha-Me-L-Cys-OH*HCl
2-Methyl-D-cysteine HCl
Alpha-Methyl-Cys-OH·HCl
(R)-2-Methylcysteine HCl
(R)-L-Α-METHYLCYSTEINE·HCL
L-2-Methylcysteine hydrochloride
2-Methyl-L-cysteine Hydrochloride
(R)-2-METHYLCYSTEINE HYDROCHLORIDE
(R)-2-Methylcysteine hydrochloride, tech
L-Cysteine, 2-Methyl-,hydrochloride (1:1)
2-Methyl-L-cysteine hydrochloride, 98% ee
(R)-2-METHYLCYSTEINE HYDROCHLORIDE USP/EP/BP
2-Methyl-L-cysteine hydrochloride, 98%, 98% ee
(R)-2-AMino-3-Mercapto-2-Methylpropanoic acid hydrochloride
(R)-2-Amino-3-mercapto-2-methyl-propionic acid hydrochloride
(2R)-2-Amino-2-methyl-3-sulfanyl-propanoic acid hydrochloride
[Molecular Formula]

C4H10ClNO2S
[MDL Number]

MFCD08063384
[MOL File]

148766-37-4.mol
[Molecular Weight]

171.65
Chemical PropertiesBack Directory
[Melting point ]

155-157℃
[storage temp. ]

Inert atmosphere,2-8°C
[solubility ]

Methanol (Slightly), Water (Slightly)
[form ]

Powder
[color ]

White to pale yellow
[Stability:]

Hygroscopic
[InChI]

InChI=1/C4H9NO2S.ClH/c1-4(5,2-8)3(6)7;/h8H,2,5H2,1H3,(H,6,7);1H/t4-;/s3
[InChIKey]

MAGCVRLGTQSVGF-NDILARRWNA-N
[SMILES]

[C@@](C)(CS)(N)C(O)=O.Cl |&1:0,r|
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[HS Code ]

2930909899
Hazard InformationBack Directory
[Uses]

2-Methyl-?L-cysteine Hydrochloride is used in the preparation of isoteric thiazoline-oxazole largazole analogs which display cytoxicity. Also used in the synthesis of 2,3-diubstituted thiazoline for pharmaceutical synthesis.
[Application]

(R)-2-Methylcysteine hydrochloride is used as a pharmaceutical intermediate component in the synthesis of Largazole, a potent class I selective histone deacetylase (HDAC) inhibitor prodrug with anticancer activity against solid tumours in preclinical models.
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