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148805-91-8

148805-91-8 Structure

148805-91-8 Structure
IdentificationBack Directory
[Name]

L-Lysine, glycyl-L-tyrosyl-N6-[N-[2-[[2-[bis(carboxymethyl)amino]ethyl](carboxymethyl)amino]ethyl]-N-(carboxymethyl)glycyl]-
[CAS]

148805-91-8
[Synonyms]

L-Lysine, glycyl-L-tyrosyl-N6-[N-[2-[[2-[bis(carboxymethyl)amino]ethyl](carboxymethyl)amino]ethyl]-N-(carboxymethyl)glycyl]-
[Molecular Formula]

C31H47N7O14
[MOL File]

148805-91-8.mol
[Molecular Weight]

741.74
Chemical PropertiesBack Directory
[Boiling point ]

1177.1±65.0 °C(Predicted)
[density ]

1.433±0.06 g/cm3(Predicted)
[pka]

1.67±0.10(Predicted)
[Sequence]

Gly-Tyr-Lys-DTPA
Hazard InformationBack Directory
[Uses]

Pendetide is a chelating agent, can be conjugated with Indium (111In) Capromab for further diagnostic use. Capromab pendetide is a FDA-approved imaging agent for the detection of soft tissue metastases in prostate carcinoma[1]. Pendetide can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
[References]

[1] Ganesh V Raj, et al. Clinical utility of indium 111-capromab pendetide immunoscintigraphy in the detection of early, recurrent prostate carcinoma after radical prostatectomy. Cancer. 2002 Feb 15;94(4):987-96. PMID:11920467
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