| Identification | Back Directory | [Name]
CGP 53820 | [CAS]
149267-24-3 | [Synonyms]
CGP 53820
L-Valine, N-acetyl-, 2-[(2S,3S)-3-[[(2S)-2-(acetylamino)-3-methyl-1-oxobutyl]amino]-2-hydroxy-4-phenylbutyl]-2-(cyclohexylmethyl)hydrazide
(2S)-2-acetamido-N-[(2S,3S)-4-[[[(2S)-2-acetamido-3-methylbutanoyl]amino]-(cyclohexylmethyl)amino]-3-hydroxy-1-phenylbutan-2-yl]-3-methylbutanamide | [Molecular Formula]
C31H51N5O5 | [MDL Number]
MFCD00917067 | [MOL File]
149267-24-3.mol | [Molecular Weight]
573.77 |
| Hazard Information | Back Directory | [Description]
Cgp 53820 is a pseudosymmetric inhibitor of HIV-1 Protease. | [Uses]
CGP 53820 is an inhibitor for HIV protease, inhibits the complex of HIV-1 and HIV-2 protease with Ki of 9 and 53 nM for HIV-1 protease and HIV-2 protease. CGP 53820 can be used in AIDS research[1]. | [References]
[1] Priestle JP, et al., Comparative analysis of the X-ray structures of HIV-1 and HIV-2 proteases in complex with CGP 53820, a novel pseudosymmetric inhibitor. Structure. 1995 Apr 15;3(4):381-9. DOI:10.1016/s0969-2126(01)00169-1 |
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CHEMICAL LAND21
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