| Identification | Back Directory | [Name]
simfibrate | [CAS]
14929-11-4 | [Synonyms]
CLY-503
Sinfibrate
simfibrate
Cholesolvin
simfibrate USP/EP/BP
1,3-Propanediol bis[2-(4-chlorophenoxy)-2-methylpropionate]
Propane-1,3-diyl bis(2-(4-chlorophenoxy)-2-methylpropanoate)
Bis[2-(4-chlorophenoxy)-2-methylpropanoic acid] 1,3-propanediyl
Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, 1,1'-(1,3-propanediyl) ester
3-[2-(4-chlorophenoxy)-2-methylpropanoyl]oxypropyl 2-(4-chlorophenoxy)-2-methylpropanoate | [EINECS(EC#)]
238-998-7 | [Molecular Formula]
C23H26Cl2O6 | [MDL Number]
MFCD00865760 | [MOL File]
14929-11-4.mol | [Molecular Weight]
469.358 |
| Hazard Information | Back Directory | [Originator]
Cholesorbin,Takeda,Japan,1971 | [Definition]
ChEBI: Simfibrate is an organic molecular entity. | [Manufacturing Process]
A mixture of 22 grams of α-(p-chlorophenoxy)isobutyric acid, 3.8 grams of
1,3-propanediol, 0.5 gram of p-toluenesulfonic acid and 150 ml of xylene was
refluxed. When the theoretically calculated amount of water had been
removed, the xylene solution was washed with dilute aqueous sodium
bicarbonate and then the xylene was distilled off. The residue was distilled
under reduced pressure to give 11 grams (47% yield) of 1,3-propanediol
bis[α-(p-chlorophenoxy)isobutyrate] boiling at 197° to 200°C/0.03 mm Hg. | [Therapeutic Function]
Antihyperlipidemic |
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