| Chemical Properties | Back Directory | [Boiling point ]
734.5±60.0 °C(Predicted) | [density ]
1.31±0.1 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
6.80±0.70(Predicted) |
| Hazard Information | Back Directory | [Description]
Isomorellinol induces apoptosis in cholangiocarcinoma (CCA)cells which is mediated through a mitochondria-dependent signaling pathway. | [Uses]
Isomorellinol is a xanthone with an anticancer potency. Isomorellinol induces apoptosis in cholangiocarcinoma cells. Isomorellinol increases the Bax/Bcl-2 protein expression ratio and decreases survivin protein expression in cholangiocarcinoma cells[1]. | [References]
[1] Hahnvajanawong C, et al. Apoptotic activity of caged xanthones from Garcinia hanburyi in cholangiocarcinoma cell lines. World J Gastroenterol. 2010 May 14;16(18):2235-43. DOI:10.3748/wjg.v16.i18.2235 |
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Biorbyt Ltd.
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+44 (0)1223 859 353 |
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http://www.biorbyt.com |
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