| Identification | Back Directory | [Name]
isopropyl((R)-(((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate | [CAS]
1496551-77-9 | [Synonyms]
MK-3682
IDX21437
IDX-21437
EOS-61179
IDX 21437
Uprifosbuvir
Uprifosbuvir (MK-3682)
D-Alanine, N-[[P(R),2'R]-2'-chloro-2'-deoxy-2'-methyl-P-phenyl-5'-uridylyl]-, 1-methylethyl ester
propan-2-yl (2R)-2-[[[(2R,3R,4R,5R)-4-chloro-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate
isopropyl((R)-(((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate | [Molecular Formula]
C22H29ClN3O9P | [MOL File]
1496551-77-9.mol | [Molecular Weight]
545.91 |
| Hazard Information | Back Directory | [Uses]
Uprifosbuvir is an antiviral agent. Uprifosbuvir is a NS5b inhibitor developed for the research of chronic hepatitis C virus[1]. | [References]
[1] Klapars A, et al. Efficient synthesis of antiviral agent uprifosbuvir enabled by new synthetic methods. Chem Sci. 2021;12(26):9031-9036. DOI:10.1039/d1sc01978c |
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