| Identification | Back Directory | [Name]
Sacubitril Impurity 7 | [CAS]
149709-44-4 | [Synonyms]
LBQ657
LCZ696-4
Sacubitrilat
Deethyl Sakuba
LCZ-696 Impurity 1
Diacid of Sacubitril
LCZ696 Impurity 900-04
Sacubitrilat (LBQ-657)
Sacubitril Desethyl Impurity
Sacubitril metabolite LBQ 657
(2R,4S)-4-(3-carboxypropanoylamino)-2-methyl-5-(4-phenylphenyl)pentanoic acid
(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(3-carboxypropanamido)- 2-methylpentanoic aci
[1,1'-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-, (αR,γS)-
4-[[(1S,3R)-1-[([1,1'-Biphenyl]-4-yl)methyl]-3-methyl-4-hydroxy-4-oxobutyl]amino]-4-oxobutanoic acid | [Molecular Formula]
C22H25NO5 | [MDL Number]
MFCD00921225 | [MOL File]
149709-44-4.mol | [Molecular Weight]
383.44 |
| Chemical Properties | Back Directory | [Boiling point ]
705.4±60.0 °C(Predicted) | [density ]
1?+-.0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
4.59±0.23(Predicted) |
| Hazard Information | Back Directory | [Uses]
Desethyl Sacubitril is an impurity in the synthesis of Sacubitril (S080895), an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure. |
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Molsyns Research
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+91-9586858886 +91-9586858886 |
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www.molsyns.com |
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