| Identification | Back Directory | [Name]
2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE | [CAS]
149847-77-8 | [Synonyms]
2-MPMDQ
2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE
Imidazo[1,2-c]quinazolin-5(3H)-one, 2,6-dihydro-2-[[4-(2-methoxyphenyl)-1-piperazinyl]methyl]-6-methyl- | [Molecular Formula]
C23H27N5O2 | [MDL Number]
MFCD00673888 | [MOL File]
149847-77-8.mol | [Molecular Weight]
405.49 |
| Hazard Information | Back Directory | [Uses]
2-MPMDQ is a novel class of α1-adrenoceptor antagonists and acts as an anti-hypertensive agent. | [Definition]
ChEBI: 2-[[4-(2-methoxyphenyl)-1-piperazinyl]methyl]-6-methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5-one is a member of piperazines. | [Biological Activity]
Potent and selective α 1 -adrenoceptor antagonist; hypotensive. | [References]
[1]. chern jw, tao pl, yen mh, et al. studies on quinazolines. 5. 2,3-dihydroimidazo[1,2-c]quinazoline derivatives: a novel class of potent and selective alpha 1-adrenoceptor antagonists and antihypertensive agents. j med chem, 1993, 36(15): 2196-2207. |
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