| Identification | Back Directory | [Name]
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(2E)-3-(2-thienyl)-2-propen-1-ylidene]- | [CAS]
1502813-63-9 | [Synonyms]
PI3K IN C96
PI3K-IN-C96
PI3K inhibitor C 96
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(2E)-3-(2-thienyl)-2-propen-1-ylidene]- | [Molecular Formula]
C11H8N2O3S | [MOL File]
1502813-63-9.mol | [Molecular Weight]
248.26 |
| Hazard Information | Back Directory | [Description]
PI3K inhibitor C 96 is an inhibitor of phosphatidylinositol 3-kinase (PI3K). It displays potent activity against multiple myeloma in vitro and in vivo. | [Uses]
PI3K-IN-7 (Compound C96) is a PI3K inhibitor. PI3K-IN-7 inhibits phosphorylation of AKT and the activation of an AKT downstream protein. PI3K-IN-7 induces apoptosis of the tumor cells. PI3K-IN-7 has low toxicity for normal cells. PI3K-IN-7 can be used for research of acute and chronic leukemia, multiple myeloma, lymphoma[1]. | [References]
[1] Mao Xinliang, et al. PI3K small-molecule inhibitor and application thereof. CN103405437A. |
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