| Identification | Back Directory | [Name]
N-SUCCINIMIDYL 7-METHOXYCOUMARIN-3-CARBOXYLATE | [CAS]
150321-92-9 | [Synonyms]
SUCCINIMIDYL 7-METHOXYCOUMARIN-3-CARBOXYLATE
N-SUCCINIMIDYL 7-METHOXYCOUMARIN-3-CARBOXYLATE
N-Succinimidyl 7-Methoxycoumarin-3-carboxylate >
7-Methoxycoumarin-3-carbonic acid N-succinimidyl ester
7-METHOXYCOUMARIN-3-CARBOXYLIC ACID, SUCCINIMIDYL ESTER
7-METHOXYCOUMARIN-3-CARBOXYLIC ACID N-SUCCINIMIDYL ESTER
2,5-Dioxopyrrolidin-1-yl 7-methoxy-2-oxo-2H-chromene-3-carboxylate
N-Succinimidyl 7-methoxycoumarin-3-carboxylate
7-Methoxycoumarin-3-carboxylic acid, succinimidyl ester *CAS 150321-92-9*
2H-1-Benzopyran-3-carboxylic acid, 7-methoxy-2-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
7-METHOXYCOUMARIN-3-CARBOXYLIC ACID N-SUCCINIMIDYL ESTER;N-SUCCINIMIDYL 7-METHOXYCOUMARIN-3-CARBOXYLATE | [Molecular Formula]
C15H11NO7 | [MDL Number]
MFCD00467593 | [MOL File]
150321-92-9.mol | [Molecular Weight]
317.25 |
| Questions And Answer | Back Directory | [Preparation]
The preparation of N-SUCCINIMIDYL 7-METHOXYCOUMARIN-3-CARBOXYLATE is as follows:
Method 1: Under magnetic stirring, 1 mmol of dimethylformamide (5 ml) and N-hydroxysuccinimide (115 mg, 1 mmol) were added to a solution of 7-methoxycoumarin-3-carboxylic acid. The mixture was cooled to -10 °C and held for 1 hour, and then N,N'-dicyclohexylcarbodiimide (226.96 mg, 1.1 mmol) was added. The mixture was stirred at -10 °C for 1 hour, and then stirred at room temperature for 3 hours. The mixture was then filtered to remove dicyclohexylurea (DCU), and then a mixture of isopropanol/hexane (1/10) was added to precipitate the product. After filtration and vacuum drying, N-SUCCINIMIDYL 7-METHOXYCOUMARIN-3-CARBOXYLATE was obtained. 1H NMR (DMSO-d6)δppm: 8.76 (2H, s); 7.57 (1H, d, J=8.5Hz); 6.95 (1H, d, J=8.5Hz); 6.85 (1H, s); 3.95 (3H, s); 3.34 (2H, s), 2.90 (4H, s). |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C
| [solubility ]
DMF: soluble
| [form ]
powder to crystal | [color ]
White solid | [λmax]
358 nm (MeOH) | [BRN ]
9145767 | [Biological Applications]
Analyzing/screening
peptides; monitoring proteolysis; quantifying
analytes;as ligands and/or substrates for transport
proteins;as a substrate formeasuring extracellular matrix
metalloprotease (MMP-1) activity,reverse transcriptase
(RT) polymerase activity, proteases activity;viscosity
sensor;colloidal diagnostic devices;useful for
synthesizing peptides | [Major Application]
Silica particles/beads | [InChI]
InChI=1S/C15H11NO7/c1-21-9-3-2-8-6-10(14(19)22-11(8)7-9)15(20)23-16-12(17)4-5-13(16)18/h2-3,6-7H,4-5H2,1H3 | [InChIKey]
JMQAALOXLOSYCQ-UHFFFAOYSA-N | [SMILES]
C1(=O)OC2=CC(OC)=CC=C2C=C1C(ON1C(=O)CCC1=O)=O | [CAS DataBase Reference]
150321-92-9 |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
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