| Identification | Back Directory | [Name]
EOSIN-5-MALEIMIDE | [CAS]
150322-02-4 | [Synonyms]
EOSIN-5-MALEIMIDE
5-MALEIMIDO-EOSIN
Eosin-5-MaleiMide [5-MaleiMido-eosin]
5-Maleimidoeosin, Fluorescent triplet probe
5-Maleimido-eosin for fluorescence, >=93% (HPLC)
1-(2',4',5',7'-tetrabromo-3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-yl)pyrrole-2,5-dione
1H-Pyrrole-2,5-dione, 1-(2',4',5',7'-tetrabromo-3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)- | [Molecular Formula]
C24H9Br4NO7 | [MDL Number]
MFCD00213878 | [MOL File]
150322-02-4.mol | [Molecular Weight]
742.95 |
| Chemical Properties | Back Directory | [Boiling point ]
773.9±60.0 °C(Predicted) | [density ]
2.50±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [form ]
powder | [pka]
6.92±0.20(Predicted) | [color ]
light orange to dark orange || light red | [InChI]
1S/C24H9Br4NO7/c25-13-6-11-21(17(27)19(13)32)35-22-12(7-14(26)20(33)18(22)28)24(11)10-2-1-8(5-9(10)23(34)36-24)29-15(30)3-4-16(29)31/h1-7,32-33H | [InChIKey]
YRCLWXRIEYQTAV-UHFFFAOYSA-N | [SMILES]
Oc1c(Br)cc2c(Oc3c(Br)c(O)c(Br)cc3C24OC(=O)c5cc(ccc45)N6C(=O)C=CC6=O)c1Br |
| Hazard Information | Back Directory | [Description]
5-Maleimido-eosin is a thiol-reactive fluorescent probe that can be used as a phosphorescent probe or as photosensitizers. | [Uses]
Eosin-5-maleimide has been used as a fluorescent probe for the human erythrocyte band 3 protein. It is widely used as a diagnostic probe for the laboratory detection of hereditary spherocytosis (HS) by flow cytometry. The eosin-5-maleimide binding test was done to analyze the effect of alectinib (first line of treatment) for anaplastic lymphoma kinase (ALK). |
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