| Identification | Back Directory | [Name]
4-[[3',4'-(METHYLENEDIOXY)BENZYL]AMINO]-6-METHOXYQUINAZOLINE | [CAS]
150450-42-3 | [Synonyms]
N-(1,3-BENZODIOXOL-5-YLMETHYL)-6-METHOXY-4-QUINAZOLINAMINE
4-[[3',4'-(METHYLENEDIOXY)BENZYL]AMINO]-6-METHOXYQUINAZOLINE
4-Quinazolinamine, N-(1,3-benzodioxol-5-ylmethyl)-6-methoxy-
N-(benzo[d][1,3]dioxol-5-ylmethyl)-6-methoxyquinazolin-4-amine | [Molecular Formula]
C17H15N3O3 | [MDL Number]
MFCD00236426 | [MOL File]
150450-42-3.mol | [Molecular Weight]
309.32 |
| Chemical Properties | Back Directory | [Boiling point ]
504.4±45.0 °C(Predicted) | [density ]
1.372±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: 5mg/mL | [form ]
solid | [pka]
5.53±0.50(Predicted) | [color ]
white |
| Hazard Information | Back Directory | [Uses]
Potent and specific inhibitor of cGMP-specific phosphodiesterase (PDE V, IC50 = 230 nM). Elevates the intracellular cGMP level without causing a change in the cAMP level in isolated porcine coronary arteries. Has no effect on other PDE isoenzymes. | [Definition]
ChEBI: N-(1,3-benzodioxol-5-ylmethyl)-6-methoxy-4-quinazolinamine is a member of quinazolines. | [Biological Activity]
Primary Target
CGMP-PDEV |
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Struchem Co., Ltd.
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0512-63009836 18994340901 |
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http://www.beidapharma.com |
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Merck KGaA
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www.sigmaaldrich.cn |
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